Already I felt better seeing the sun out when I woke. I’m stoked it’s going to be heaps warmer in the days ahead too.
My head felt clearer and the intense headache was way down from yesterday. AND I felt hungry. All good signs my body is recovering well from the Cyclophosphamide.
If you don’t know this chemo, it is an alkylating agent and in the nitrogen mustard family of medications. I understand the mechanism of action is that it disrupts the cellular DNA making it impossible for cells to reproduce. The cells go into programmed cellular death (apoptosis). The body must then breakdown the remnants of these dead cells which create byproducts.
One of the byproducts (acrolein) is toxic to the bladder epithelium and hemorrhagic cystitis can develop. This is why it’s been so imperative to drink the exact amount of water along with electrolytes to assist the process of passing this out. It’s been hurting to pee (as a result) the last several days, but it didn’t hurt this morning so I hope that means I’m out of the red zone as far as developing hemorrhagic cystitis.
I should mention that this drug isn’t particularly selective which cells it attacks so while it’s depleting all of my white blood cells, it also destroys some red blood cells and platelets. This may have more of an affect on me next week and my recovery. We will see how it goes….
8am meds today:
I felt well enough to eat some protein by the afternoon. Fernie and I put together a platter of roast chicken with baby potatoes, mushrooms, garlic, onions, homemade salsa verde, and a side of fried local vegetables. I was proud of myself; I ate almost the whole plate (not literally ;-).
Other than that, I’m trying to plan out my next week. I have to figure out when my hair is going to be shaved off. It’s best done before I get immune compromised (very weak) and potentially quite sick after the weekend. Plus I want to have it removed properly to donate to charity. I’m thinking this Friday might be the big day.
8pm medication: Ondansetron 8 mg
Video of Filgrastim Shot